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Why do we take selective serotonin reuptake inhibitors (SSRIs) for anxiety and depression, instead of just taking serotonin? ELI5ish.

Sarah Jenkins
Sarah Jenkins
Lead Content Curator · Mar 30, 2026 · Updated Apr 13, 2026

A *very* ~~convoluted~~ ELI5ish explanation. Serotonin is a messenger molecule that causes many different reactions. Let say that cells are like machines with switches, messenger molecules switch them on for some time before they switch back off.

142
Words

1 min
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#29
of 500 in Psychology

+109%
vs Category Avg

The Short Answer

A *very* ~~convoluted~~ ELI5ish explanation. Serotonin is a messenger molecule that causes many different reactions. Let say that cells are like machines with switches, messenger molecules switch them on for some time before they switch back off. Serotonin works on many switches in different parts of the body – bowl movement, sleep, mood, blood clotting, memory, learning – flooding the system with serotonin would turn all of them on and it wouldn't be good. However these switches are not all the same and what we can do is change how they work. SSRI basically turn on the switch for a longer period of time or make it so that it takes less serotonin to switch it on in the first place. Because the switches are different we can change how one work, but everything else keeps more or less the same.

Analysis

Key Concepts: Serotonin, switches, switch

This explanation focuses on serotonin, switches, switch and spans 142 words across 7 sentences. At 109% above the average Psychology explanation (68 words), this is one of the more thorough answers in this category, reflecting the complexity of the underlying question.

What This Answer Covers

The explanation opens with: “A *very* ~~convoluted~~ ELI5ish explanation.” It then elaborates by presenting a contrasting perspective, ultimately building toward a complete picture across 7 connected points.

How This Compares in Psychology

Ranked #29 of 500 Psychology questions by answer depth (top 7%). This places it in the comprehensive tier — the top quarter of most thoroughly answered questions. Questions at this depth typically involve multi-faceted topics requiring nuanced explanation.

Frequently Asked Questions

Is there a simple explanation for why we take selective serotonin reuptake inhibitors (ssris) for anxiety and depression, instead of just taking serotonin? eli5ish.?

A *very* ~~convoluted~~ ELI5ish explanation. Serotonin is a messenger molecule that causes many different reactions. Let say that cells are like machines with switches, messenger molecules switch them on for some time before they switch back off….

How detailed is this explanation compared to similar Psychology questions?

This is one of the most thorough answer at 142 words, ranked #29 of 500 Psychology questions by depth. The key concepts covered are serotonin, switches, switch.

What approach does this answer take to explain we take selective serotonin reuptake inhibitors (ssris) for ?

The explanation uses root cause analysis and contrasting perspectives across 142 words. It is categorized under Psychology and addresses the question through 2 analytical lenses.